Fig. 2
From: Elucidating the role of the gut microbiota in the physiological effects of dietary fiber
Effects of AX and MCC supplementation on satiety and surrogate endpoints. Principal component analysis plots show A perceived satiety and surrogate endpoints at baseline and B their percentage change from baseline per AX and MCC groups. Line graphs show weekly SLIM scale ratings C 30–60 min after consuming a meal with AX or MCC and D upon awakening. Bars (insets) represent the area under the SLIM score curve (AUCBL–W6). Scatter plots show E HOMA-IR, F QUICKI, G fecal calprotectin, and H TNF-α at baseline and week 6 of AX or MCC supplementation, respectively. Bars (insets) represent the percent change from baseline values per group. To assess within-group changes relative to baseline, data were analyzed for C and D using repeated measures one-way ANOVA with permutations and for E to H using paired permutational t-tests. To assess between-group differences, data were analyzed for A and B using permutational multivariate analysis of variance based on Manhattan distance and for C to H using unpaired permutational t-tests. Statistical significance was set for A to D at p < 0.05 and for E to H at p < 0.01. Data for C to H presented as mean ± SD; for E to H symbols represent individual samples. AX, arabinoxylan; HOMA-IR, homeostatic model assessment of insulin resistance; MCC, microcrystalline cellulose; QUICKI, quantitative insulin sensitivity check index; SLIM, Satiety Labeled Intensity Magnitude; TNF-α, tumor necrosis factor-α