Fig. 1

Body-site specific virus ecology after lung transplantation (sample numbers: n_L = 28, n_P = 28). A Shannon diversities of lung and blood derived viruses in LTRs, 56 BALF and plasma samples collected from 14 patients on the same day, species level annotation. Distribution differences between body-sites **p < 0.01, Wilcoxon-Mann-Whitney test. B Chao1 richness index of lung and blood derived virome (matched samples as above). Distribution difference **p < 0.01, Wilcoxon-Mann-Whitney test. C Change of viral sequence abundance in matched BALF and plasma samples facetted by time after lung transplantation (5–12 weeks, 13–34 weeks, 35–95 weeks). Sequencing counts were normalized against total metagenome counts and individual viral genome sizes, the resulting abundance indices were 4th root transformed [Aziz et al Front Microbiol 2015]. **p < 0.01, ***p < 0.001. D Inter-sample dissimilarity within (W) and between (B) body sites facetted by time after transplantation (matched samples as above). Shown are Bray-Curtis dissimilarities among samples and body-site specific sample centroids. Filled circles indicate plasma, white circles BALF samples. P values are depicted, Wilcoxon-Mann-Whitney test