Fig. 2

Concatenated protein trees for dissimilatory sulfate reduction pathways. A Concatenated protein tree showing the diversity of bacteria that possess genes for the final enzyme of the dissimilatory sulfate reduction pathway — dsrAB. B Concatenated protein tree showing the diversity of bacteria that possess genes for anaerobic sulfite reductase (asrABC), an enzyme also capable of dissimilatory sulfate reduction. Gray clades only contain reference sequences, darker gray clades contain reference sequences and sequences from this study. Bracketed numbers indicate the sequence origin within each clade: (number of sequences from our study, number of sequences from references). Bacterial genera (dsr) or orders (asr) originating from study samples are bolded. Pie charts indicate the disease state associated with sequences within each clade with blue indicating healthy, yellow adenoma, and maroon carcinoma. Clades outlined in black contain Fusobacterium sequences