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Fig. 3 | Microbiome

Fig. 3

From: Altered gut metabolites and microbiota interactions are implicated in colorectal carcinogenesis and can be non-invasive diagnostic biomarkers

Fig. 3

Metagenomic data profiles and diagnostic performances. A Non-metric multidimensional scaling (NMDS) analysis on the Bray-Curtis distance from bacterial species abundances for CRC, CRA and NC groups. B Heatmap of 44 differentially abundant bacterial species between CRC and NC. C Heatmap of 45 differentially abundant bacterial species between CRC and CRA. Differentially abundant species were determined using Wilcoxon rank-sum test for the relative abundance data, with cut-off: FDR adjusted p < 0.05, mean of relative abundance > 0.001 and prevalence rate > 0.4. CRC; colorectal cancer, CRA; colorectal adenoma, NC; normal control. D Receiver operating characteristic (ROC) analysis for the 6 bacteria discriminating CRC from NC. E ROC analysis for the 14 bacteria markers discriminating CRA from NC. F ROC analysis for the 6 bacteria markers discriminating CRC from CRA. CRC; colorectal cancer, CRA; colorectal adenoma, NC; normal control

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Microbiome

ISSN: 2049-2618

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