Fig. 2
From: Substantial overlap between symptomatic and asymptomatic genitourinary microbiota states
The genitourinary microbiota composition of asymptomatic patients fluctuates. a Relative abundance of microbiota in samples collected at three consecutive time points (T1, T2, T3) from 10 asymptomatic volunteers. b Principal coordinate analysis of the microbiota composition in the three urine specimens collected from 10 symptomatic volunteers (n = 30). Points are colored by patient and subsequently collected samples are collected via lines. c Principal coordinate analysis based on functional pathway abundance determined via HUMAnN2 in the longitudinal urine specimens collected from 10 symptomatic volunteers (n = 26). Four samples did not yield sufficient functional resolution and were excluded before analysis. Points are colored by patient and subsequently collected samples are collected via lines. d Bray-Curtis distance of the microbiota composition of subsequently collected urine specimens from asymptomatic volunteers (intra-personal) compared to the distance between patients collected from different individuals at the same timepoint (inter-personal). Bray-Curtis distances between groups for each interval were compared using the Wilcoxon signed-rank test with *P < 0.05