The bacterial density of clinical rectal swabs is highly variable, correlates with sequencing contamination, and predicts patient risk of extraintestinal infection

Table 5 Multivariable frailty model of features associated with bacterial infection

	Hazard ratio (95% CI)	P value
log (copies 16S/sample)	1.21 (1.067–1.378)	0.003**
SOFA Score	0.99 (0.866–1.125)	0.845
Charlson Comorbidity Index	1.02 (0.947–1.092)	0.650
VRE colonization	0.63 (0.308–1.298)	0.211
Piperacillin-tazobactam	2.32 (0.899–5.986)	0.082
Admission diagnosis of sepsis	2.20 (0.981–4.944)	0.056
Number of events = 37	Likelihood ratio test: p <2*10⁻⁸	Concordance: 0.857

ISSN: 2049-2618