Biogeographic traits of dimethyl sulfide and dimethylsulfoniopropionate cycling in polar oceans

Microbiome

Table 1 A list of key enzymes involved in DMS/DMSP cycling

Substrate	End product	Key enzyme	Function	Pathway	Polypeptide class	Ref
Met	DMSP	DSYB	MTHB methyltransferase	DMSP biosynthesis	SAM-dependent methyltransferase, Pfam family (PF10672)	[8]
		TpMMT	MTHB methyltransferase		SAM-dependent methyltransferase, Pfam family (PF10672)	[9]
		DsyB	MTHB methyltransferase		SAM-dependent methyltransferase, Pfam family (PF10672)	[10]
		MmtN	Met methyltransferase		Class I SAM-dependent methyltransferase family (PF10672)	[11]
DMSP	DMS	Alma1	DMSP lyase	DMSP cleavage	Aspartate racemase superfamily	[7]
		DddD			Class III acetyl CoA-transferase family	[12]
		DddL			Cupin family	[13]
		DddY				[14]
		DddQ				[15]
		DddK				[16]
		DddW				[17]
		DddP			M24B metallopeptidase family	[18]
	MeSH	DmdA	DMSP demethylase	DMSP demethylation	Glycine cleavage system T family	[19]
DMSO	DMS	DMSOR	DMSO reductase	DMSO reduction	DMSO reductase family	[3]
DMS	DMSO	Tmm	TMA monooxygenase	DMS oxidation	Class B flavoprotein monooxygenases	[20]
		DsoABCDEF	Monooxygenase		Phenol hydroxylase subunit super family	[21]
		DdhABC	DMS dehydrogenase		DMSO reductase family	[22]
	MeSH	DmoAB	DMS monooxygenase	DMS oxidation	Flavin-linked monooxygenases, luciferase family	[23]
MeSH	DMS	MddA	SAM-dependent methyltransferase	MeSH transmethylation	SAM-dependent methyltransferase, Pfam family (PF10672)	[24]

Enzymes originated from eukaryotes are shown in regular text and those from bacteria are highlighted in bold. MTHB methylthiohydroxybutryate, Met methionine, DMSP dimethylsulfoniopropionate, DMSO dimethyl sulfoxide, TMA trimethylamine, SAM S-adenosyl methionine

ISSN: 2049-2618