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Fig. 4 | Microbiome

Fig. 4

From: Commensal microbe-derived acetate suppresses NAFLD/NASH development via hepatic FFAR2 signalling in mice

Fig. 4

Bacteroides acidifaciens and Blautia producta produce acetate from the fermentation of inulin. ad SCFA concentrations Bacteroides acidifaciens (BA), Blautia producta (BP), or BA/BP mixture (mix)-administered mice. The mice were fed a diet containing cellulose (a, c) or inulin (b, d) as a source of dietary fibre for 4 weeks. SCFA content of the faeces in mice (a BA, n = 4; BP, n = 4, mix, n = 4; b BA, n = 4; BP, n = 4, mix, n = 5). SCFA content of the caecal contents (c BA, n = 4; BP, n = 4, mix, n = 4; d BA, n = 4; BP, n = 4, mix, n = 5). Each point represents an individual mouse (thick bars, means; error bars, SEM). *P < 0.05, **P < 0.01, ***P < 0.001 (Kruskal-Wallis followed by Steel-Dwass test)

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