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Fig. 4 | Microbiome

Fig. 4

From: Review: microbial transformations of human bile acids

Fig. 4

Pathways of CA and CDCA epimerization, including corresponding EC identifiers. A CA undergoes three different epimerization pathways leading to the production of iCA (via 3α/β-HSDH), UCA (via 7α/β-HSDH), or 12-ECA (via 12α/β-HSDH) while B CDCA undergoes two distinct epimerization pathways leading to the production of UDCA (via 7α/β-HSDH) or iCDCA (via 3α/β-HSDH). *S. maltophilia transforms CDCA to 7-oxo-CDCA but the enzyme is categorized under EC 1.1.1.159, where the official reaction involves CA 7α-oxidation [70]

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Microbiome

ISSN: 2049-2618

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