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Fig. 5 | Microbiome

Fig. 5

From: Genetic and behavioral adaptation of Candida parapsilosis to the microbiome of hospitalized infants revealed by in situ genomics, transcriptomics, and proteomics

Fig. 5

Presence of C. parapsilosis affects bacterial community member’s expression. A PCA of C. parapsilosis in situ and pure culture transcriptomes. B Depiction of features identified by sPLS-DA for separating C. parapsilosis in situ and pure culture transcriptomes. Plotted are the feature weights. Black bars are genes that exhibited higher expression on average in situ whereas grey had higher average expression in culture. Genes labeled in red correspond to proteins of unknown function. C, D PCAs of E faecalis (C) and S. epidermidis (D) transcriptomes from infant microbiomes both with and without detected C. parapsilosis. Candida-negative transcriptomes were from four different infants (published previously; Sher et al. 2020) denoted as 64, 66, 69, and 71

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Microbiome

ISSN: 2049-2618

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