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Fig. 4 | Microbiome

Fig. 4

From: Genetic and behavioral adaptation of Candida parapsilosis to the microbiome of hospitalized infants revealed by in situ genomics, transcriptomics, and proteomics

Fig. 4

C. parapsilosis displays distinct and highly variable in situ transcriptomic profiles. A Hierarchical clustering of C. parapsilosis TPM values for C1_006 in in situ samples and pure culture samples under a variety of conditions. B Average log2 fold change in situ vs culture plotted against the mean of normalized counts for each transcript. Transcripts in red were identified as being significantly differentially expressed by DESeq2. C Boxplots of expression of categories of genes involved in biofilm formation. Gene lists and categories were obtained from [27]. Regulatory defective mutants refers to regulatory genes that inhibit biofilm formation when mutated, regulatory enhanced refer to genes that increase biofilm formation when mutated, and unknown refers to genes involved in biofilm formation but their exact role is unclear

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