Fig. 5

Changes in serum levels of amino acids and lipids associated with metabolic phenotypes. a Correlation matrix between metabolite consensus modules and host phenotypes measured in mice described in Fig. 1. Modules were determined based on patterns of co-abundance of metabolites using weighted correlation network analysis (WGCNA). Each of the modules was labelled with a unique color as an identifier. Each module was tested for correlation with host metabolic phenotypes. Within each cell, upper values are correlation coefficients between module and the phenotypes; lower values are the corresponding FDR adjusted-P values. b Pathways enriched in the blue, turquoise, and red modules as determined by Fisher’s test