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Fig. 1 | Microbiome

Fig. 1

From: Assessment of the microbiome during bacteriophage therapy in combination with systemic antibiotics to treat a case of staphylococcal device infection

Fig. 1

Microbiota analysis of a patient undergoing adjunctive phage therapy, and analysis of patient samples with respect to intensive care unit (ICU) patients, a subset of the American Gut Project (AGP) population that have taken antibiotics within the past week, and a subset of the AGP population who have not taken antibiotics in the past year. a Patient microbiota profile. A principal coordinate plot of unweighted UniFrac distances of skin (forehead, blue; nares, green; axilla, red;), oral (mouth, orange), and fecal (stool, purple) samples from phage patient. b Comparison of alpha diversity across sample type. Shannon’s diversity for skin (forehead, nares, axilla), oral (mouth), and fecal (stool) samples from phage patient. Boxplots are showing the quartiles (25th and 75th percentiles) on the box, and ± 1.5 interquartile ranges for the whiskers. P-values of pairwise Kruskal-Wallis testing are shown for fecal samples compared to other sample types on the figure. A complete list of p-values for pairwise comparisons of each sample type is provided in supplementary file. c Comparative microbiota analyses. A principal coordinate plot of unweighted UniFrac distances of phage patient (orange) skin (ring), oral (diamond), and fecal (sphere) samples in the context of ICU (green) and AGP (purple or yellow) samples. The sample type is denoted by shape, while sample cohort is denoted by the different colors, within the plot

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