Fig. 1
From: Separating the signal from the noise in metagenomic cell-free DNA sequencing
Algorithm design and application to metagenomic sequencing of urinary cfDNA. a Diagram of the major components of the LBBC workflow. b Genus-level bacterial cfDNA (in RGE, see bar) across 44 urinary cfDNA samples from a kidney transplant cohort. Samples (columns) are grouped by clinical diagnosis (EN, Enterococcus; EC, E. coli; Neg., negative) and sex of subject. Rows are individual genera detected. c Abundance matrix after application of LBBC