Fig. 8
From: Toothbrush microbiomes feature a meeting ground for human oral and environmental microbiota
Significant associations between metadata and relative abundances of bacterial species (a) or RPKMs of ARGs (b) in toothbrush microbiomes based on Hierarchical All-against-All association (HAllA) testing. All metadata presented in Fig. 4 (n = 20 variables) were included in the HAllA analyses and those with significant association (q < 0.1) to at least one taxon/ARG are presented in the respective figure panels (i.e., 12/20 and 7/20 variables associated with particular taxa and ARGs, respectively). Significant clusters of related features (q < 0.1) are outlined and ranked based on hierarchy of similarity scores. Grid color intensity corresponds to normalized mutual information similarity metric. Sidebar colors in b correspond to the ARG drug class