Antimicrobial-specific response from resistance gene carriers studied in a natural, highly diverse microbiome

Microbiome

Table 2 Effect of antimicrobial treatment, dosages, and sample type (DNA or RNA) on bacterial community structure (β-diversity). A complementary statistical analysis was conducted in order to identify factors with a significant effect on the bacterial community

Factor	Microbial community similarities
Factor	R² value	P value
All datasets
Antimicrobials	0.265	0.001*
Dosage	0.076	0.001*
Type	0.043	0.001*
Colistin dataset
Dosage (D)	0.528	0.001*
Type (T)	0.069	0.001*
D × T	0.131	0.001*
Tetracycline dataset
Dosage (D)	0.471	0.001*
Type (T)	0.065	0.007*
D × T	0.097	0.087
Alkylpyrazine dataset
Dosage (D)	0.340	0.001*
Type (T)	0.134	0.001*
D × T	0.128	0.011*
Glyphosate dataset
Dosage (D)	0.255	0.001*
Type (T)	0.070	0.001*
D × T	0.099	0.769

ISSN: 2049-2618