Next-generation diagnostics: virus capture facilitates a sensitive viral diagnosis for epizootic and zoonotic pathogens including SARS-CoV-2

Table 1 Viral pathogens causing notifiable or emerging epizootic and zoonotic diseases, their nucleic acids, number of genomes or genome segments, and baits represented on the VirBaits set. The percentage of baits on the VirBaits set is given for each virus (compare Fig. 1)

Viral pathogen	Nucleic acid	Number of genomes	Baits number	Baits %
African horse sickness virus	dsRNA	196	1940	1.1
African swine fever virus	dsDNA	20	10,763	6.1
Bovine herpesvirus 1	dsDNA	26	2400	1.4
Lumpy skin disease virus	dsDNA	11	2629	1.5
Monkeypox virus	dsDNA	52	9631	5.4
Sheeppox virus/goatpox virus	dsDNA	9	1078	0.6
Suid alphaherpesvirus 1	dsDNA	26	3635	2.0
Bluetongue virus	dsRNA	175	8971	5.1
Epizootic hemorrhagic disease virus	dsRNA	31	1287	0.7
Borna disease virus/Bornaviridae	ssRNA	94	3279	1.8
Bovine leukemia virus	ssRNA	73	416	0.2
Bovine viral diarrhea virus 1, 2	ssRNA	198	7966	4.5
Classical swine fever virus	ssRNA	102	3134	1.8
Crimean-Congo hemorrhagic fever virus	ssRNA	182	5165	2.9
Ebolavirus	ssRNA	1368	7116	4.0
Equine encephalitis virus	ssRNA	635	5944	3.3
Equine infectious anemia virus	ssRNA	25	635	0.4
Foot-and-mouth disease virus	ssRNA	549	12,821	7.2
Hendra henipavirus	ssRNA	18	902	0.5
Influenza A virus	ssRNA	12,608	55,649	31.4
Newcastle disease virus	ssRNA	391	10,630	6.0
Nipah henipavirus	ssRNA	21	1141	0.6
Rabies lyssavirus	ssRNA	494	11,476	6.5
Rift Valley fever virus	ssRNA	167	539	0.3
Rinderpest virus	ssRNA	9	671	0.4
SARS-CoV-2	ssRNA	33	2196	^a
Schmallenberg virus	ssRNA	11	198	0.1
Small ruminant morbillivirus	ssRNA	71	1513	0.9
Swine vesicular disease virus	ssRNA	16	380	0.2
Vesicular stomatitis Indiana virus	ssRNA	48	2409	1.4
West Nile virus	ssRNA	1156	3167	1.8

ISSN: 2049-2618