Shifts in microbial diversity, composition, and functionality in the gut and genital microbiome during a natural SIV infection in vervet monkeys

Table 1 Factors associated with microbial community composition based on Adonis analysis

Variable	R² value	Unadjusted p value	Adjusted p value
All samples
Developmental stage	0.037	0.002	< 0.001
Sex	0.011	0.018	0.003
Province	0.021	0.017	< 0.001
Source	0.316	< 0.001	< 0.001
Animal ID	0.347	< 0.001	< 0.001
Age category	0.053	0.008	< 0.001
SIV	0.011	0.043	0.18
Rectal samples
Developmental stage	0.027	0.118	0.4012
Sex	0.010	0.147	0.326
Province	0.052	< 0.001	< 0.001
Age category	0.079	0.129	0.385
SIV	0.010	0.173	0.256
Fecal samples
Developmental stage	0.076	0.463	0.4144
Sex	0.012	0.519	0.934
Province	0.051	0.442	0.418
Age Category	0.123	0.534	0.527
SIV	0.044	0.076	0.067
Vaginal samples
Developmental stage	0.045	0.305	0.401
Province	0.155	< 0.001	< 0.001
Age category	0.055	0.091	0.201
SIV	0.015	0.339	0.413
Penile samples
Developmental stage	0.100	0.051	0.028
Province	0.169	< 0.001	0.001
Age Category	0.136	0.141	0.218
SIV	0.035	0.479	0.656
Acute/chronic samples
Source	0.418	< 0.001	< 0.001
Age category	0.015	0.118	0.297
Sex	0.004	0.288	0.356
Province	0.061	< 0.001	< 0.001

The effects of age (developmental stage or dental age category), sex, geography (province or geographic site), individual, body site, and SIV infection status on variation in microbial communities

ISSN: 2049-2618