Fig. 3
From: Freshwater viral metagenome reveals novel and functional phage-borne antibiotic resistance genes
![Fig. 3](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs40168-020-00863-4/MediaObjects/40168_2020_863_Fig3_HTML.png)
Maximum-likelihood phylogenetic tree of HRV-1 with representative enzymes of classes A, C, and D β-lactamases. Numbers at the nodes represent bootstrap values based on 100 re-samplings, and values higher than 80% are shown. Metagenome sequences used for the tree construction, marked with blue circles, were selected from the Han River bacterial metagenome. Accession numbers for the representative sequence types of β-lactamases used for phylogenetic analyses are listed in Table S3