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Table 1 Clinical characteristics of the human samples

From: Gut bacterial ClpB-like gene function is associated with decreased body weight and a characteristic microbiota profile

 

Without obesity

With obesity

 
 

(n = 55)

(n = 76)

p value

Females n (%)

37 (67.3)

52 (68.4)

0.519

Age (years)

53.7 [17.4]

48.6 [15.7]

0.188

BMI (kg/m2)

24.9 (2.5)

43.2 (6.8)

< 0.001

Waist (cm)

89.7 (9.6)

126.2 (14.1)

< 0.001

Fat total (%)

32.5 (7.5)

49.6 (5.6)

< 0.001

Android fat (%)

32.6 (10.5)

56.5 (5.4)

< 0.001

Gynoid fat mass (%)

37.5 [15.6]

50.6 [8.7]

< 0.001

SBP (mmHg)

124.0 (16.1)

139.2 (19.3)

< 0.001

DBP (mmHg)

71.1 (11.0)

78.0 (10.9)

0.001

Glucose (mg/dL)

95.0 [13.0]

96.0 [13.5]

0.284

HbA1c (%)

5.5 (0.3)

5.6 (0.3)

0.016

Cholesterol (mg/dL)

200.0 [48.0]

183.5 [57.0]

0.043

LDL-cholesterol (mg/dL)

119.0 [48.0]

112.0 [58.8]

0.634

HDL-cholesterol (mg/dL)

63.9 (17.5)

53.5 (12.0)

0.005

Triglycerides (mg/dL)

79.0 [39.0]

111.5 [75.0]

< 0.001

hsCRP (mg/dL)

0.7 [0.9]

4.9 [7.2]

< 0.001

K03695 (AU)

1.6 × 10−1 (3.0 × 10−2)

1.4 × 10−1 (2.4 × 10−2)

8.0 × 10−6

  1. Results are expressed as number and frequencies for categorical variables, mean and standard deviation (SD) for normal distributed continuous variables, and median and interquartile range [IQR] for non-normal distributed continuous variables. To determine differences between study groups, we used χ2 for categorical variables, unpaired Student’s t test in normal quantitative, and Mann-Whitney U test for non-normal quantitative variables. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HbA1c glycated hemoglobin, LDL low density lipoprotein, HDL high density lipoprotein, hsCRP high-sensitive C-reactive protein, AU arbitrary units
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Microbiome

ISSN: 2049-2618

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