Fig. 6

Effects of selected metabolites on the inhibition of V. cholerae growth in vitro. N16961, a 7th pandemic V. cholerae strain, was grown in the presence of indicated metabolites in M9 media. A total of 17 metabolites were tested. Medium pH was neutralized by adding NaOH or HCl, when necessary. OD₆₀₀ values were measured to monitor bacterial growth every 2 h. M9 media contains 0.4% glucose as a primary carbon source. Lines in gray show bacterial growth in M9+glucose (M9G), while black lines indicate bacterial growth in M9G supplemented with indicated metabolites. Cholic acid (panel k), Butyric acid (panel l), Isobutyric acid (panel m), Propionic acid (panel n), Valeric acid (panel o), Isovaleric acid (panel p), and Trimethylamine (panel q) are highly capable of inhibiting N16961 growth