Fig. 1
From: Pregnancy and lactation interfere with the response of autoimmunity to modulation of gut microbiota
Lack of beneficial response to vancomycin in PP MRL/lpr mice. a Study design. PP mice were mated at 8 weeks of age, and only those delivered at 11 weeks old (± 1 day) were used in this study. Oral vancomycin was initiated at 9 weeks of age and ended at 15 weeks (endpoint). b Spleen and mesenteric lymph node (MLN) weights at 15 weeks of age. c Relative level of anti-DNA IgG in the mouse serum at 15 weeks of age. d Level of proteinuria over time. e Renal glomerular and tubulointerstitial (TI) scores. In b–e, n ≥ 7 in each group. *p < 0.05, **p < 0.01, n.s. not statistically significant