Fig 4.

Nine scenarios of the behavior of Accumulibacter (metatranscriptomic pattern and chemical parameters) in response to all environmental conditions (balance of carbon, electron, and energy flows) with specific strategies proposed to balance the carbon and phosphorus feeding to optimize reactor operation. Number labels of modules: 1, acetate uptake; 2, PHA module; 3, LCFA module; 4, AA module; 5, glutamine/glutamate in N module; 6, Gly module; 7, complete TCA cycle; 8, reductive branch of split TCA cycle; 9, oxidative branch of split TCA cycle; 10, partial TCA cycle; 11, denitrification and dissimilatory nitrogen reduction in N module; 12, hydrogenases; 13, PolyP module; 14, phosphorus transporters (pst and pit); 15, ETP; 16, PL module; 17, EPS module; 18, transformation of acetate to pyr