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Fig. 4 | Microbiome

Fig. 4

From: Haem iron reshapes colonic luminal environment: impact on mucosal homeostasis and microbiome through aldehyde formation

Fig. 4

Correlation between metabolomic and physiological data. a Relevance networks representing the stronger correlations (higher than 0.65) between 25 metabolites and 12 animal physiological traits (metadata) selected with rCCA. The edge colours indicate the nature of the correlation (positive in red, negative in blue). Metabolites and metadata are represented respectively as white and grey rectangles. b Boxplot of the area under the curve of the NMR spectra for selected metabolites that covariated with lipoperoxidation status. P < 0.05 using ANOVA. Holm-Sidak’s multiple comparison test: *versus CON, μversus Ca, #versus HEM. Haem, haem in faecal water; BodyW, body weight; UK3, unknown compound; 4HPP, 3-(4-hydroxyphenyl)propionic acid; ba6, unknown bile acid

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