Fig. 1

Phyla (a), genera (b), and species (c) showing significant differences in fecal metagenome profiles when comparing BD patients with healthy controls. Differentially abundant phylotypes were identified by Wilcoxon rank sum test (FDR < 0.1, corrected by the Benjamini and Hochberg for multiple comparisons). Only the top 5 phyla and top 10 genera are shown. The phylotypes enriched in healthy group are colored red. The relative abundance was shown by boxplot. Boxes represent the inter quartile ranges, lines inside the boxes denote medians, and ‘+’ denotes means