Skip to main content

Table 1 Socio-demographic and microbiological characteristics of subjects

From: Increased richness and diversity of the vaginal microbiota and spontaneous preterm birth

Characteristics Term pregnancies (n = 170) Preterm pregnancies (n = 46) p value
Age (mean ± SD, range)1 33.6 ± 4.2 (21–45) 33.65 ± 4.1 (25–45) 0.948
 21–25 5 (2.9%) 1 (2.1%)  
 26–35 114 (67.1%) 32 (69.5%)
 36–45 51 (30.0%) 13 (28.2%)
BMI (mean ± SD, range)1 22.9 ± 3.8 (17–40) 24.2 ± 5.6 (19–43) 0.125
 Underweight (< 18.50) 7 (4.1%) 0 (0%)  
 Normal weight (18.51–24.9) 131 (77.0%) 33 (73.3%)
 Overweight (25.0–29.9) 25 (14.7%) 8 (17.7%)
 Obese (> 30) 7 (4.1%) 4 (9.0%)
 MD3 0 (0%) 1 (2.2%)
Ethnicity2 0.261
 White 108 (63.5%) 22 (47.8%)  
 East Asian 26 (15.3%) 6 (13.0%)
 South/Southeast Asian 15 (8.8%) 4 (8.7%)
 Latin America/Hispanic 8 (4.7%) 3 (6.5%)
 Black 3 (1.8%) 2 (4.4%)
 Other/mixed ethnicity 10 (5.9%) 6 (13.0%)
 MD 0 (0%) 3 (6.5%)
Community state type (CST)2 0.361
 I 56 (32.9%) 17 (37%)  
 II 9 (5.3%) 5 (10.9%)
 III 28 (16.5%) 8 (17.4%)
 IVA 31 (18.2%) 6 (13%)
 IVC 19 (11.2%) 2 (4.3%)
 IVD 11 (6.5%) 1 (2.2%)
 V 16 (9.4%) 7 (15.2%)
Estimated bacterial load (log copies of 16S rRNA gene)/swab (mean ± SD, range)1 7.78 ± 0.93 (4.89–10.67) 8.07 ± 0.71 (6.32–10.33) 0.049
Presence of Mollicutes2 68 (40%) 28 (60.8%) 0.012
Presence of Ureaplasma2 40 (23.4%) 14 (30.4%) 0.337
U. parvum 37 (21.7%) 14 (30.4%)  
U. urealyticum 3 (1.7%) 0 (0%)
Shannon diversity (mean ± SD, range)1 1.28 ± 0.86 (0.13–4.52) 1.81 ± 1.13 (0.34–5.16) 0.004
Chao1 richness (mean ± SD, range)1 36.22 ± 14.80 (14.39–115.74) 46.38 ± 24.19 (20.20–126.01) 0.009
  1. 1t test; 2chi-square; 3MD = missing data