Table 6 Replication study in the LUKAS cohort: bacterial OTUs and fungal taxa identified in the HOTES study, with significant differences (p < 0.05; Kruskal-Wallis test after Bonferroni correction) in relative abundance in house dust of homes categorized by moisture damage severity and extent of visible mold in the LUKAS cohort (75th Pctl, 75th percentile; moisture damage: 0 … no moisture damage, 1 … minor moisture damage, 2 … major moisture damage; visible mold: 0 … no visible mold, 1 … spots of visible mold, 2 … visible mold; N, number of homes)
From: Indoor microbiota in severely moisture damaged homes and the impact of interventions
| Â | Â | Â | Â | Moisture damage | Visible mold | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Taxonomy | Â | Â | Relative abundance | Â | Â | Â | Relative abundance | Â | ||||
OTU ID | Family | Genus | Species | Â | N | Median | 75th Pctl | p value | Â | N | Median | 75th Pctl | p value |
Bacterial OTUs | |||||||||||||
324217 | Nocardioidaceae | Aeromicrobium | 0 | 116 | 8.74 × 10−5 | 2.65–10−4 |  | 0 | 251 | 1.09 × 10−4 | 2.96 × 10−4 |  | |
|  |  |  |  | 1 | 151 | 1.07 × 10−4 | 2.49 × 10−4 |  | 1 | 61 | 1.31 × 10−4 | 2.93 × 10−4 |  |
|  |  |  |  | 2 | 142 | 2.37 × 10−4 | 4.59 × 10−4 | <0.001 | 2 | 97 | 2.07 × 10−4 | 3.93 × 10−4 | 0.214 |
279515 | Intrasporangiaceae | Phycicoccus |  | 0 | 116 | 0 | 1.55 × 10−4 |  | 0 | 251 | 0 | 1.67 × 10−4 |  |
|  |  |  |  | 1 | 151 | 7.02 × 10−5 | 2.44 × 10−4 |  | 1 | 61 | 7.94 × 10−5 | 2.06 × 10−4 |  |
|  |  |  |  | 2 | 142 | 9.11 × 10−5 | 3.37 × 10−4 | 0.349 | 2 | 97 | 1.31 × 10−4 | 4.14 × 10−4 | 0.007 |
Fungal taxa | |||||||||||||
– | Chaetomiaceae | Humicola | nigrescens | 0 | 111 | 0 | 3.80 × 10−4 |  | 0 | 247 | 0 | 5.28 × 10−4 |  |
|  |  |  |  | 1 | 149 | 5.28 × 10−5 | 6.31 × 10−4 |  | 1 | 56 | 5.97 × 10−5 | 4.49 × 10−4 |  |
|  |  |  |  | 2 | 136 | 2.45 × 10−4 | 8.82 × 10−4 | 0.014 | 2 | 93 | 3.57 × 10−4 | 1.22 × 10−3 | <0.001 |