Fig. 5

Bacterial co-occurrence network revealed the key role of Lactobacillus spp. in formation of bacterial correlation network in intestinal microbiota. Co-occurrence network of the control group (density = 0.329, centralization = 0.475; a), the antibiotic group (density = 0.213, centralization = 0.335; b) and the probiotic group (density = 0.355, centralization = 0.364; c) are shown. Lactobacillus spp. are highlighted as blue circle, while those genera directly correlated with Lactobacillus spp. are colored as green. The width of gray lines is proportional to Spearman correlation coefficient, while the type of lines represents the type of interaction (solid line: positive correlation; dash line: negative correlation)