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Table 2 Partial correlations between class-level taxa and brain regions controlling for total gray matter volume in IBS (N = 29)

From: Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome

Brain region Firmicutes-associated Bacilli Firmicutes-associated Clostridia Bacteroidetes-associated Bacteroidia
  r p r p r p
Subcortical
 L thalamus −.15 .461 −.40 .037 .36 .063
 L caudate nucleus .28 .156 .49 .010 −.45 .017
 L putamen .18 .376 .52 .006 −.53 .005
 R putamen .11 .600 .42 .029 −.48 .012
 L pallidum .30 .132 .37 .056 −.44 .023
 R pallidum .35 .070 .36 .069 −.45 .019
 L NACC .20 .326 .38 .052 −.45 .019
 R NACC .42 .029 .53 .004 −.59 .001
 R CeB −.20 .306 −.34 .080 .41 .032
Insula
 Horizontal ramus of the anterior segment of the lateral sulcus .15 .462 −.42 .027 .35 .069
 R short insular gyrus −.12 .535 −.51 .007 .44 .023
 Vertical ramus of the anterior segment of the lateral sulcus −.20 .325 −.48 .012 .49 .009
Frontal
 R Orbital part of the inferior frontal gyrus −.43 .025 −.43 .027 .49 .009
 R orbital gyrus −.44 .020 −.39 .043 .47 .013
 R gyrus rectus −.34 .083 −.47 .014 .46 .015
 R superior part of the precentral gyrus −.23 .252 −.42 .031 .41 .033
 L triangular part of the inferior frontal gyrus .46 .017 −.10 .604 .05 .790
Cingulate  
 Posterior-ventral part of the cingulate gyrus −.39 .043 −.11 .580 .07 .716
Parietal
 R supramarginal gyrus .50 .008 .27 .167 −.28 .159
 L_parietal occipital sulci .01 .969 −.50 .008 .45 .018
Temporal
 L temporal pole −.39 .046 −.21 .284 .24 .228
 L planum polare of the superior temporal gyrus −.07 .747 .41 .035 −.37 .060
 L lateral occipital temporal sulcus −.02 .924 .45 .018 −.44 .021
Occipital
 L superior and transvers occipital sulci .28 .153 .39 .043 −.45 .017
  1. Pearson’s correlation between relative abundance and brain volumes
  2. R=correlation, p=probability
  3. P values less than .05 uncorrected are bolded