Outcome | Method |
K
u
|
K
0.5
|
K
w
|
K
BC
|
---|
Overall Survival | Uncorrected | 0.049 | 0.008 | 0.065 | 0.029 |
| Corrected | 0.046 | 0.007 | 0.065 | 0.022 |
Grade III aGVHD | Uncorrected | 0.496 | 0.514 | 0.472 | 0.849 |
| Corrected | 0.560 | 0.575 | 0.518 | 0.933 |
-
p values from MiRKAT-S using the weighted (K
w) and unweighted (K
u) UniFrac kernels, the generalized UniFrac kernel with α=0.5 (K
0.5), and the Bray-Curtis kernel (K
BC) with outcomes of overall survival and severe (at least grade 3) graft-versus-host disease. “Corrected” indicates the p values are based on the modified score statistic with proper type I error; “uncorrected” indicates the p values are based on the original score statistic