Table 5 Comparison of relative abundance of selected (selection based on overall statistical significance across all clinical groups, determined by Kruskal-Wallis test with p < 0.05) bacterial species across the four clinical subgroups

Actinomyces spp.^a

0.019 ± 0.052

0.035 ± 0.043

0.001 ± 0.005

0.015 ± 0.023

Anaerostipes spp.^ba

0.248 ± 0.498

2.040 ± 2.235

0.123 ± 0.157

0.395 ± 0.793

Papillibacter spp.

0

0.025 ± 0.067

0

0

Blautia spp.^ba

1.130 ± 1.923

6.505 ± 5.909

0.450 ± 0.366

1.975 ± 4.392

Lauconostoc spp.^ac

0.035 ± 0.058

0.002 ± 0.006

0.063 ± 0.101

0.005 ± 0.012

Eggerthella spp.^a

0.018 ± 0.058

0.112 ± 0.189

0.003 ± 0.010

0.008 ± 0.015

Weissella spp.

0.038 ± 0.066

0.003 ± 0.011

0.090 ± 0.172

0.002 ± 0.006

Bifidobacterium spp.^ba

2.440 ± 8.130

3.915 ± 5.362

0.408 ± 1.039

4.195 ± 9.828

Allisonella spp.

0.008 ± 0.028

0

0.016 ± 0.049

0.149 ± 0.443

Bifidobacteriaceae, Other spp.

0.038 ± 0.156

0.025 ± 0.032

0.003 ± 0.013

0.085 ± 0.254

Streptococcus spp.^a

1.276 ± 2.612

0.643 ± 0.657

0.192 ± 0.273

0.595 ± 1.476

Lachnospiracea_incertae_sedis spp.^a

2.092 ± 3.592

2.600 ± 1.666

0.813 ± 0.769

1.206 ± 1.048

p_Bacteria, Other spp.^bd

4.893 ± 5.681

1.858 ± 2.906

3.481 ± 3.747

2.700 ± 6.159

Clostridium XI spp.^a

0.224 ± 0.378

0.911 ± 0.761

0.255 ± 0.505

0.312 ± 0.511

Eubacterium spp.

0.004 ± 0.013

0.046 ± 0.105

0.004 ± 0.013

0.015 ± 0.038

Acinetobacter spp.

0.017 ± 0.036

0.002 ± 0.006

0.031 ± 0.106

0

Dialister spp.^a

0.227 ± 0.727

1.997 ± 4.464

3.799 ± 11.633

4.292 ± 6.127

Gordonibacter spp.

0.005 ± 0.012

0.012 ± 0.029

0

0.002 ± 0.006

Canternibacter spp.

0.004 ± 0.016

0

0.154 ± 0.546

0.046 ± 0.126

Oxalobacteraceae, Other spp.

0.049 ± 0.080

0.006 ± 0.017

0.050 ± 0.095

0.022 ± 0.072

Olsenella spp.

0

0

0.006 ± 0.023

0

Alistipes spp.^b

6.142 ± 5.326

1.975 ± 2.507

5.473 ± 5.802

4.992 ± 5.512

Clostridium IV spp.^c

0.829 ± 1.501

0.495 ± 0.438

1.037 ± 1.373

0.277 ± 0.400