Skip to main content

Table 1 Permutational multivariate analysis of variance (PERMANOVA) tests of the bacterial gut microbiota on the unweighted and weighted UniFrac distances and the Bray-Curtis dissimilarity according to individuals’ health status and constipation

From: Altered gut microbiota in Rett syndrome

  Metric F R 2 p value*
HC (n = 29)
vs
RTT (n = 50)
Unweighted UniFrac 6.84 0.08 ≤0.003
  Weighted UniFrac 15.6 0.16 ≤0.003
  Bray-Curtis 6.94 0.08 ≤0.003
HC (n = 29)
vs
RTT-C (n = 34)
Unweighted UniFrac 5.59 0.08 ≤0.003
  Weighted UniFrac 12.1 0.16 ≤0.003
  Bray-Curtis 5.39 0.08 ≤0.003
HC (n = 29)
vs
RTT-NC (n = 14)
Unweighted UniFrac 5.27 0.11 ≤0.003
  Weighted UniFrac 8.75 0.17 ≤0.003
  Bray-Curtis 5.47 0.11 ≤0.003
RTT-C (n = 34)
vs
RTT-NC (n = 14)
Unweighted UniFrac 1.31 0.02 0.180
  Weighted UniFrac 1.10 0.02 0.687
  Bray-Curtis 1.76 0.03 0.180
  1. HC healthy controls, RTT-C constipated Rett syndrome subjects, RTT-NC non-constipated Rett syndrome subjects
  2. *Bonferroni corrected p values