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Table 1 Taxa contributing to the classification of child versus adult gut communities

From: Structure and function of the healthy pre-adolescent pediatric gut microbiome

Analysis type Taxon identity (OTU or species) Random forests importance score Mean relative abundance (%)a White’s non-parametric t-test
Child Adult p value q value
16S OTU_1555 Anaerovorax 6.77 0.23 0.16 9.99E−04 0.028
16S OTU_1412 Bifidobacterium 6.07 0.34 0.01 9.99E−04 0.028
16S OTU_1015 Faecalibacterium 5.28 8.26 3.52 9.99E−04 0.028
16S OTU_411 Collinsella 4.79 0.20 0.01 9.99E−04 0.028
16S OTU_2162 Lachnospiraceae Incertae Sedis 4.74 0.93 0.28 9.99E−04 0.028
16S OTU_2956 Porphyromonadaceae 4.69 0.01 0.08 9.99E−04 0.028
16S OTU_3384 Bacteroides 4.24 0.08 0.20 9.99E−04 0.028
16S OTU_4352 Lachnospiraceae 4.04 3.52 1.65 1.99E−03 0.053
16S OTU_1928 Ruminococcaceae 3.60 0.38 0.08 9.99E−04 0.028
16S OTU_987 Ruminococcaceae 3.53 0.57 0.09 9.99E−04 0.028
WGS Bifidobacterium longum 6.01 6.54 0.24 9.99E−04 0.018
WGS Eggerthella lenta 5.44 0.06 0.01 1.00 1.000
WGS Porphyromonas asaccharolytica 5.13 6.30E−03 0.03 4.92E−01 0.888
WGS Clostridium asparagiforme 5.13 1.24E−02 6.67E−03 1.00 1.000
WGS Streptococcus sanguinis 4.64 0.01 4.09E−04 1.00 1.000
WGS Faecalibacterium prausnitzii 4.63 7.39 1.31 9.99E−04 0.018
WGS Faecalibacterium cf 4.56 4.47 0.68 9.99E−04 0.018
WGS Bifidobacterium catenulatum 4.37 0.33 0.02 8.40E−03 0.069
WGS Gordonibacter pamelaeae 3.94 0.21 0.01 6.30E−02 0.313
WGS Granulicatella adiacens 3.76 1.00E−03 6.36E−06 1.00 1.000
  1. Taxa were identified as a function of their Random Forests permutation importance values. OTU identities were generated using the RDP Classifier with a confidence threshold of 50 %, and species identities were generated from the shotgun metagenomic libraries using MetaPhlAn. Differences in the relative abundance of each taxon were evaluated using two-tailed White’s non-parametric t-test, and Storey’s false discovery rate estimator was used to correct for multiple testing corrections within each data set (i.e., 16S, WGS)
  2. a n = 37 children and 43 adults in the OTU-based analysis and 22 children and 22 adults in the WGS-based analysis
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