Figure 5

Changes in individual bacterial abundance at each clinical transition. (A) Relative abundance of Pseudomonas at baseline and exacerbation. Each point represents a different patient labeled with patient ID. The dotted line has a slope of 1. Points to the left of the 1 line indicate an increase in Pseudomonas at exacerbation compared to baseline; points to the right of the 1 line indicate a decrease in Pseudomonas. Coefficient estimates of each genus for (B) baseline to exacerbation, (C) exacerbation to treatment and (D) treatment to recovery. The top 12 genera from Figure 2 and genera with coefficient estimate significantly different than 1 (P < 0.05) are shown. Bars indicate mean coefficient estimate; error bars indicate 95% confidence interval of the mean.