Skip to main content

Table 3 Changes of cytokine gene expression in antibiotic treated, Helicobacter hepaticus uninfected mice compared to untreated, uninfected controls

From: The effects of intestinal microbial community structure on disease manifestation in IL-10-/- mice infected with Helicobacter hepaticus

 

Vancomycin

 

One-day recovery from cefoperazone

 

Six-week recovery from cefoperazone

 

Cytokines

H. hepaticus uninfected

SD

H. hepaticus uninfected

SD

H. hepaticus uninfected

SD

INFg

1.13

0.66

1.64

1.31

-3.78

1.10*

IL12a

1.13

0.83

8.88

0.64*

-3.58

1.10*

TNF

1.28

0.21

1.56

0.27

1.64

6.12

IL4

1.13

0.58

1.96

1.07

-1.6

1.1

IL13

1.60

0.21

9.25

0.83*

1.51

1.1

IL5

1.13

0.58

-21.48

1.36*

-1.6

1.1

TGF

-1.05

0.59

-51.09

1.36*

-3.29

1.40*

IL6

1.13

0.58

-21.48

1.36*

-1.6

1.1

FOXp3

1.13

0.58

-21.48

1.36*

-1.6

1.1

Il17a

1.68

1.16

-4.98

1.28*

-1.72

1.1

IL23

-1.05

0.48

4.92

0.62*

-1.6

1.1

Cxcl2

2.26

1.15

-5.76

2.35*

-1.6

1.1

Ccl5

-1.01

0.66

-4.07

0.54*

-5.84

7.73*

Ccl2

3.15

0.87*

9.61

0.35*

-10.2

1.10*

NOS2

2.94

1.30

-2.23

0.03

-3.93

3.34*

ARG1

1.13

0.58

6.41

0*

-1.62

0.81

Chi3/4

1.13

1.19

16.45

0.26*

-13.69

1.10*

PTGS2

-1.05

0.93

1.22

0.01

2.46

4.95

INDO

1.60

0.81

-26.17

0.52*

-2.95

1.1

  1. Results are presented as mean change. *Statistically significant difference. INF, interferon; IL, interleukin; TNF, tumor necrosis factor; TGF, transforming growth factor; Foxp3, Forkhead box protein 3; NOS, nitric oxide synthase; Chi, chitinase; PTGS, prostaglandin-endoperoxide synthase; INDO, indoleamine-pyrrole 2,3-dioxygenase.