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  1. Dysregulation of gut microbiota-associated tryptophan metabolism has been observed in patients with multiple sclerosis. However, defining direct mechanistic links between this apparent metabolic rewiring and i...

    Authors: Theresa L. Montgomery, Korin Eckstrom, Katarina H. Lile, Sydney Caldwell, Eamonn R. Heney, Karolyn G. Lahue, Angelo D’Alessandro, Matthew J. Wargo and Dimitry N. Krementsov
    Citation: Microbiome 2022 10:198
  2. Most previous studies attempting to prove the phenomenon of mother-to-infant microbiota transmission were observational, performed only at genus/species-level resolution, and relied entirely on non-culture-bas...

    Authors: Zhi Zhong, Hai Tang, Tingting Shen, Xinwei Ma, Feiyan Zhao, Lai-Yu Kwok, Zhihong Sun, Menghe Bilige and Heping Zhang
    Citation: Microbiome 2022 10:197
  3. The assembly of the rhizomicrobiome, i.e., the microbiome in the soil adhering to the root, is influenced by soil conditions. Here, we investigated the core rhizomicrobiome of a wild plant species transplanted...

    Authors: Jingjing Chang, Lei Tian, Marcio F.A. Leite, Yu Sun, Shaohua Shi, Shangqi Xu, Jilin Wang, Hongping Chen, Dazhou Chen, Jianfeng Zhang, Chunjie Tian and Eiko E. Kuramae
    Citation: Microbiome 2022 10:196
  4. Vascular calcification is a major cause of the high morbidity and mortality of cardiovascular diseases and is closely associated with the intestinal microbiota. Short-chain fatty acids (SCFAs) are derived from...

    Authors: Jianlong Yan, Yanbin Pan, Wenming Shao, Caiping Wang, Rongning Wang, Yaqiong He, Min Zhang, Yongshun Wang, Tangzhiming Li, Zhefeng Wang, Wenxing Liu, Zhenmin Wang, Xin Sun and Shaohong Dong
    Citation: Microbiome 2022 10:195
  5. Seasonal breeding in mammals has been widely recognized to be regulated by photoperiod, but the association of gut microbiota with photoperiodic regulation of seasonal breeding has never been investigated.

    Authors: Hanyi Zhu, Guoliang Li, Jing Liu, Xiaoming Xu and Zhibin Zhang
    Citation: Microbiome 2022 10:194
  6. Fecal microbiota transplantation (FMT) effectively prevents the recurrence of Clostridioides difficile infection (CDI). Long-term engraftment of donor-specific microbial consortia may occur in the recipient, but ...

    Authors: Shaodong Wei, Marie Louise Jespersen, Simon Mark Dahl Baunwall, Pernille Neve Myers, Emilie Milton Smith, Jens Frederik Dahlerup, Simon Rasmussen, Henrik Bjørn Nielsen, Tine Rask Licht, Martin Iain Bahl and Christian Lodberg Hvas
    Citation: Microbiome 2022 10:193
  7. Symbionts provide a variety of reproductive, nutritional, and defensive resources to their hosts, but those resources can vary depending on symbiont community composition. As genetic techniques open our eyes t...

    Authors: Shelby E. McIlroy, Casey P. terHorst, Mark Teece and Mary Alice Coffroth
    Citation: Microbiome 2022 10:192
  8. Dioecious plants have coevolved with diverse plant microbiomes, which are crucial for the fitness and productivity of their host. Sexual dimorphism in morphology, physiology, or gene expression may relate to d...

    Authors: Qingxue Guo, Lin Liu, Jiantong Liu, Helena Korpelainen and Chunyang Li
    Citation: Microbiome 2022 10:191
  9. Viral-encoded auxiliary metabolic genes (AMGs) are important toolkits for modulating their hosts’ metabolisms and the microbial-driven biogeochemical cycles. Although the functions of AMGs have been extensivel...

    Authors: Xiao-Qing Luo, Pandeng Wang, Jia-Ling Li, Manzoor Ahmad, Li Duan, Ling-Zi Yin, Qi-Qi Deng, Bao-Zhu Fang, Shan-Hui Li and Wen-Jun Li
    Citation: Microbiome 2022 10:190
  10. In deep-sea hydrothermal vent areas, deprived of light, most animals rely on chemosynthetic symbionts for their nutrition. These symbionts may be located on their cuticle, inside modified organs, or in special...

    Authors: Johanne Aubé, Marie-Anne Cambon-Bonavita, Lourdes Velo-Suárez, Valérie Cueff-Gauchard, Françoise Lesongeur, Marion Guéganton, Lucile Durand and Julie Reveillaud
    Citation: Microbiome 2022 10:189
  11. Comparisons of the gut microbiome of lean and obese humans have revealed that obesity is associated with the gut microbiome plus changes in numerous environmental factors, including high-fat diet (HFD). Here, ...

    Authors: Gihyeon Kim, Youngmin Yoon, Jin Ho Park, Jae Won Park, Myung-guin Noh, Hyun Kim, Changho Park, Hyuktae Kwon, Jeong-hyeon Park, Yena Kim, Jinyoung Sohn, Shinyoung Park, Hyeonhui Kim, Sun-Kyoung Im, Yeongmin Kim, Ha Yung Chung…
    Citation: Microbiome 2022 10:188
  12. Gut microbiota (GM) dysregulation, known as dysbiosis, has been proposed as a crucial driver of obesity associated with “Western” diet (WD) consumption. Gut dysbiosis is associated with increased gut permeabil...

    Authors: Preeti Dinesh Virwani, Lin Cai, Patrick Ka Kit Yeung, Gordon Qian, Yingxian Chen, Lei Zhou, Jason Wing Hon Wong, Yu Wang, Joshua Wing Kei Ho, Kui Kai Lau, Pei-Yuan Qian and Sookja Kim Chung
    Citation: Microbiome 2022 10:187
  13. Phytoremediation is a potentially cost-effective way to remediate highly contaminated mine tailing sites. However, nutrient limitations, especially the deficiency of nitrogen (N), can hinder the growth of plan...

    Authors: Yongbin Li, Rui Yang, Max M. Häggblom, Mengyan Li, Lifang Guo, Baoqin Li, Max Kolton, Zhiguo Cao, Mohsen Soleimani, Zheng Chen, Zhimin Xu, Wenlong Gao, Bei Yan and Weimin Sun
    Citation: Microbiome 2022 10:186

    The Correction to this article has been published in Microbiome 2022 10:232

  14. Metagenomic data can be used to profile high-importance genes within microbiomes. However, current metagenomic workflows produce data that suffer from low sensitivity and an inability to accurately reconstruct...

    Authors: Ilya B. Slizovskiy, Marco Oliva, Jonathen K. Settle, Lidiya V. Zyskina, Mattia Prosperi, Christina Boucher and Noelle R. Noyes
    Citation: Microbiome 2022 10:185
  15. Plant cell walls are interwoven structures recalcitrant to degradation. Native and adapted microbiomes can be particularly effective at plant cell wall deconstruction. Although most understanding of biological...

    Authors: Lauren M. Tom, Martina Aulitto, Yu-Wei Wu, Kai Deng, Yu Gao, Naijia Xiao, Beatrice Garcia Rodriguez, Clifford Louime, Trent R. Northen, Aymerick Eudes, Jenny C. Mortimer, Paul D. Adams, Henrik V. Scheller, Blake A. Simmons, Javier A. Ceja-Navarro and Steven W. Singer
    Citation: Microbiome 2022 10:183
  16. The rhizosphere is a hotspot for microbial activity and contributes to ecosystem services including plant health and biogeochemical cycling. The activity of microbial viruses, and their influence on plant-micr...

    Authors: George Muscatt, Sally Hilton, Sebastien Raguideau, Graham Teakle, Ian D. E. A. Lidbury, Elizabeth M. H. Wellington, Christopher Quince, Andrew Millard, Gary D. Bending and Eleanor Jameson
    Citation: Microbiome 2022 10:181
  17. As a widely used broad-spectrum antibiotic, chloramphenicol is prone to be released into environments, thus resulting in the disturbance of ecosystem stability as well as the emergence of antibiotic resistance...

    Authors: Jiayu Zhang, Xiaoyan Li, Uli Klümper, Huaxin Lei, Thomas U. Berendonk, Fangliang Guo, Ke Yu, Chao Yang and Bing Li
    Citation: Microbiome 2022 10:180
  18. Each year, approximately 9.5 million metric tons of plastic waste enter the ocean with the potential to adversely impact all trophic levels. Until now, our understanding of the impact of plastic pollution on m...

    Authors: Amaranta Focardi, Lisa R. Moore, Jean-Baptiste Raina, Justin R. Seymour, Ian T. Paulsen and Sasha G. Tetu
    Citation: Microbiome 2022 10:179
  19. Many animals live in intimate associations with a species-rich microbiome. A key factor in maintaining these beneficial associations is fidelity, defined as the stability of associations between hosts and thei...

    Authors: Yui Sato, Juliane Wippler, Cecilia Wentrup, Rebecca Ansorge, Miriam Sadowski, Harald Gruber-Vodicka, Nicole Dubilier and Manuel Kleiner
    Citation: Microbiome 2022 10:178
  20. Process and function that underlie the assembly of a rhizosphere microbial community may be strongly linked to the maintenance of plant health. However, their assembly processes and functional changes in the d...

    Authors: Tao Wen, Penghao Xie, C. Ryan Penton, Lauren Hale, Linda S. Thomashow, Shengdie Yang, Zhexu Ding, Yaqi Su, Jun Yuan and Qirong Shen
    Citation: Microbiome 2022 10:177
  21. Amplicon sequencing is an established and cost-efficient method for profiling microbiomes. However, many available tools to process this data require both bioinformatics skills and high computational power to ...

    Authors: Ezgi Özkurt, Joachim Fritscher, Nicola Soranzo, Duncan Y. K. Ng, Robert P. Davey, Mohammad Bahram and Falk Hildebrand
    Citation: Microbiome 2022 10:176
  22. The role of the pulmonary microbiome in sarcoidosis is unknown. The objectives of this study were the following: (1) examine whether the pulmonary fungal and bacterial microbiota differed in patients with sarc...

    Authors: Kristel S. Knudsen, Sverre Lehmann, Rune Nielsen, Solveig Tangedal, Andreu Paytuvi-Gallart, Walter Sanseverino, Einar M. H. Martinsen, Pieter S. Hiemstra and Tomas M. Eagan
    Citation: Microbiome 2022 10:175
  23. The gut microbiome plays an important role in autoimmunity including multiple sclerosis and its mouse model called experimental autoimmune encephalomyelitis (EAE). Prior studies have demonstrated that the mult...

    Authors: Paola Bianchimano, Graham J. Britton, David S. Wallach, Emma M. Smith, Laura M. Cox, Shirong Liu, Kacper Iwanowski, Howard L. Weiner, Jeremiah J. Faith, Jose C. Clemente and Stephanie K. Tankou
    Citation: Microbiome 2022 10:174
  24. Ixodes scapularis is the predominant tick vector of Borrelia burgdorferi, the agent of Lyme disease, in the USA. Molecular interactions between the tick and B. burgdorferi orchestrate the migration of spirochetes...

    Authors: Sukanya Narasimhan, Nallakkandi Rajeevan, Morven Graham, Ming-Jie Wu, Kathleen DePonte, Solenne Marion, Orlanne Masson, Anya J. O’Neal, Joao H. F. Pedra, Daniel E. Sonenshine and Erol Fikrig
    Citation: Microbiome 2022 10:173
  25. Candidatus Nanohaloarchaeota, an archaeal phylum within the DPANN superphylum, is characterized by limited metabolic capabilities and limited phylogenetic diversity and until recently has been considered to exclu...

    Authors: Yuan-Guo Xie, Zhen-Hao Luo, Bao-Zhu Fang, Jian-Yu Jiao, Qi-Jun Xie, Xing-Ru Cao, Yan-Ni Qu, Yan-Lin Qi, Yang-Zhi Rao, Yu-Xian Li, Yong-Hong Liu, Andrew Li, Cale Seymour, Marike Palmer, Brian P. Hedlund, Wen-Jun Li…
    Citation: Microbiome 2022 10:172
  26. Faecal samples are frequently used to characterise the gut microbiota in health and disease, yet there is considerable debate about how representative faecal bacterial profiles are of the overall gut community...

    Authors: Indrani Mukhopadhya, Jennifer C. Martin, Sophie Shaw, Aileen J. McKinley, Silvia W. Gratz and Karen P. Scott
    Citation: Microbiome 2022 10:171
  27. Geothermal systems have contributed greatly to both our understanding of the functions of extreme life and the evolutionary history of life itself. Shallow-sea hydrothermal systems are ecological intermediates...

    Authors: Xiaofeng Chen, Kai Tang, Mu Zhang, Shujing Liu, Mingming Chen, Peiwen Zhan, Wei Fan, Chen-Tung Arthur Chen and Yao Zhang
    Citation: Microbiome 2022 10:170
  28. Chinese Lunar Palace 1 (LP1) is a ground-based bio-regenerative life support system (BLSS) test bed integrating highly efficient plant cultivation, animal protein production, urine nitrogen recycling, and bioc...

    Authors: Jianlou Yang, Zikai Hao, Lantao Zhang, Yuming Fu and Hong Liu
    Citation: Microbiome 2022 10:169
  29. Both the gut microbiota and chronic viral infections have profound effects on host immunity, but interactions between these influences have been only superficially explored. Cytomegalovirus (CMV), for example,...

    Authors: Ning Chin, Nicole R. Narayan, Gema Méndez-Lagares, Amir Ardeshir, W. L. William Chang, Jesse D. Deere, Justin H. Fontaine, Connie Chen, Hung T. Kieu, Wenze Lu, Peter A. Barry, Ellen E. Sparger and Dennis J. Hartigan-O’Connor
    Citation: Microbiome 2022 10:168
  30. The rumen is an ecosystem with a complex microbial microflora in which microbes initiate biofilm formation by attaching to plant surfaces for plant degradation and are capable of converting feed to nutrients a...

    Authors: Xiaozhen Liu, Qinmeng Liu, Sihuai Sun, Hengxi Sun, Yao Wang, Xihui Shen and Lei Zhang
    Citation: Microbiome 2022 10:167
  31. Healthier ruminant products can be achieved by adequate manipulation of the rumen microbiota to increase the flux of beneficial fatty acids reaching host tissues. Genomic selection to modify the microbiome fun...

    Authors: Marina Martínez-Álvaro, Jennifer Mattock, Marc Auffret, Ziqing Weng, Carol-Anne Duthie, Richard J. Dewhurst, Matthew A. Cleveland, Mick Watson and Rainer Roehe
    Citation: Microbiome 2022 10:166

    The Correction to this article has been published in Microbiome 2022 10:184

  32. SARS-CoV-2 infection causes COVID-19 disease, which can result in consequences ranging from undetectable to fatal, focusing attention on the modulators of outcomes. The respiratory tract microbiome is thought ...

    Authors: Carter Merenstein, Frederic D. Bushman and Ronald G. Collman
    Citation: Microbiome 2022 10:165
  33. Tropical members of the sponge genus Ircinia possess highly complex microbiomes that perform a broad spectrum of chemical processes that influence host fitness. Despite the pervasive role of microbiomes in Ircini...

    Authors: Joseph B. Kelly, David E. Carlson, Jun Siong Low and Robert W. Thacker
    Citation: Microbiome 2022 10:164

    The Correction to this article has been published in Microbiome 2022 10:182

  34. Mammalian intestinal microbiomes are necessary for antagonizing systemic viral infections. However, very few studies have identified whether poultry commensal bacteria play a crucial role in protecting against...

    Authors: Hai-chang Yin, Zhen-dong Liu, Wei-wei Zhang, Qing-zhu Yang, Tian-fei Yu and Xin-jie Jiang
    Citation: Microbiome 2022 10:162
  35. Microbial symbioses in marine invertebrates are commonplace. However, characterizations of invertebrate microbiomes are vastly outnumbered by those of vertebrates. Protists and fungi run the gamut of symbiosis...

    Authors: Corey C. Holt, Vittorio Boscaro, Niels W. L. Van Steenkiste, Maria Herranz, Varsha Mathur, Nicholas A. T. Irwin, Gracy Buckholtz, Brian S. Leander and Patrick J. Keeling
    Citation: Microbiome 2022 10:161
  36. Although the lack of estrogen receptor β (ERβ) is a risk factor for the development of inflammatory bowel disease (IBD) and psychiatric disorders, the underlying cellular and molecular mechanisms are not fully...

    Authors: Yuanyuan Ma, Tianyao Liu, Xin Li, Anqi Kong, Rui Xiao, Ruxin Xie, Junwei Gao, Zhongke Wang, Yun Cai, Jiao Zou, Ling Yang, Lian Wang, Jinghui Zhao, Haiwei Xu, Warner Margaret, Xingshun Xu…
    Citation: Microbiome 2022 10:160
  37. Tooth decay is one of the most prevalent diseases worldwide, and efficient tooth brushing with a fluoride-containing dentifrice is considered fundamental to caries prevention. Fluoride-containing dentifrices h...

    Authors: Miguel Carda-Diéguez, Rebecca Moazzez and Alex Mira
    Citation: Microbiome 2022 10:159
  38. The intestinal microbiota fundamentally guides the development of a normal intestinal physiology, the education, and functioning of the mucosal immune system. The Citrobacter rodentium-carrier model in germ-free ...

    Authors: Rossana Romero, Agnieszka Zarzycka, Mathieu Preussner, Florence Fischer, Torsten Hain, Jan-Paul Herrmann, Katrin Roth, Corinna U. Keber, Kushal Suryamohan, Hartmann Raifer, Maik Luu, Hanna Leister, Wilhelm Bertrams, Matthias Klein, Hosam Shams-Eldin, Ralf Jacob…
    Citation: Microbiome 2022 10:158
  39. DNA methylation in prokaryotes is involved in many different cellular processes including cell cycle regulation and defense against viruses. To date, most prokaryotic methylation systems have been studied in c...

    Authors: Hoon Je Seong, Simon Roux, Chung Yeon Hwang and Woo Jun Sul
    Citation: Microbiome 2022 10:157
  40. Many insects house symbiotic intracellular bacteria (endosymbionts) that provide them with essential nutrients, thus promoting the usage of nutrient-poor habitats. Endosymbiont seclusion within host specialize...

    Authors: Mariana Galvão Ferrarini, Elisa Dell’Aglio, Agnès Vallier, Séverine Balmand, Carole Vincent-Monégat, Sandrine Hughes, Benjamin Gillet, Nicolas Parisot, Anna Zaidman-Rémy, Cristina Vieira, Abdelaziz Heddi and Rita Rebollo
    Citation: Microbiome 2022 10:156
  41. The large intestine is a colonization site of beneficial microbes complementing the nutrition of cattle but also of zoonotic and animal pathogens. Here, we present the first global gene catalog of cattle fecal...

    Authors: S. Teseo, S. Otani, C. Brinch, S. Leroy, P. Ruiz, M. Desvaux, E. Forano, F. M. Aarestrup and P. Sapountzis
    Citation: Microbiome 2022 10:155
  42. Complex interactions between the gut microbiome and immune cells in infancy are thought to be part of the pathogenesis for the marked rise in pediatric allergic diseases, particularly food allergies. Food prot...

    Authors: Victoria M. Martin, Yamini V. Virkud, Ehud Dahan, Hannah L. Seay, Dvir Itzkovits, Hera Vlamakis, Ramnik Xavier, Wayne G. Shreffler, Qian Yuan and Moran Yassour
    Citation: Microbiome 2022 10:154
  43. Infectious diseases have caused huge economic loss and food security issues in fish aquaculture. Current management and breeding strategies heavily rely on the knowledge of regulative mechanisms underlying dis...

    Authors: Qian Zhou, Xue Zhu, Yangzhen Li, Pengshuo Yang, Shengpeng Wang, Kang Ning and Songlin Chen
    Citation: Microbiome 2022 10:153
  44. Pneumococcal carriage has often been studied from a serotype perspective; however, little is known about the strain-specific carriage and inter-strain interactions. Here, we examined the strain-level carriage ...

    Authors: Oluwaseun Rume-Abiola Oyewole, Philipp Latzin, Silvio D. Brugger and Markus Hilty
    Citation: Microbiome 2022 10:152
  45. The role of bacterial symbionts that populate octocorals (Cnidaria, Octocorallia) is still poorly understood. To shed light on their metabolic capacities, we examined 66 high-quality metagenome-assembled genom...

    Authors: Tina Keller-Costa, Lydia Kozma, Sandra G. Silva, Rodolfo Toscan, Jorge Gonçalves, Asunción Lago-Lestón, Nikos C. Kyrpides, Ulisses Nunes da Rocha and Rodrigo Costa
    Citation: Microbiome 2022 10:151
  46. Controlling excess biomass accumulation and clogging is important for maintaining the performance of gas biofilters and reducing energy consumption. Interruption of bacterial communication (quorum quenching) c...

    Authors: Yong-Chao Wang, Yu-Ting Lin, Can Wang, Zhen Tong, Xu-Rui Hu, Ya-Hui Lv, Guan-Yu Jiang, Meng-Fei Han, Ji-Guang Deng, Hsing-Cheng Hsi and Chung-Hak Lee
    Citation: Microbiome 2022 10:150
  47. The pathogenesis of inflammatory bowel diseases (IBD) is multifactorial, and diagnostic and treatment strategies for IBD remain to be developed. RhoB regulates multiple cell functions; however, its role in col...

    Authors: Jianming Yang, Geng Pei, Xuan Sun, Yawen Xiao, Chunhui Miao, Lu Zhou, Bangmao Wang, Liu Yang, Mingyu Yu, Zhi-Song Zhang, Evan T. Keller, Zhi Yao and Quan Wang
    Citation: Microbiome 2022 10:149

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