Fig. 2

parS sites and their implications in the origin domain folding. a Schematic representation of a Hi-C contact map for a bacterial genome. The signal for each secondary diagonal (d1,d2,d3…) was computed in order to generate the graph presented below that showed the strength of the different secondary diagonals along the genome. Each graph was centered on the origin of replication. b Signal of the secondary diagonals for several OMM¹² bacteria, centered on ori (L. reuteri, B. coccoides, F. plautii, E. clostridioformis, B. caecimuris). Localization of parS sites is indicated as red dashed lines. Red stars indicate the presence of several parS sites in the same 5 kb window. c–e The contact map of L. reuteri (5 kb resolution), B. coccoides (5 kb resolution), and E. clostridioformis (5 kb resolution). ParS sites (green dashed lines), putative prophages, coverage, GC content, GC skew, and genomic coordinates are indicated below each matrix