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Fig. 1 | Microbiome

Fig. 1

From: A systematically biosynthetic investigation of lactic acid bacteria reveals diverse antagonistic bacteriocins that potentially shape the human microbiome

Fig. 1

Overview of secondary metabolite biosynthetic capacity in LAB. a Overall BGCs identified from 31,977 LAB genomes. The numbers outside the brackets indicate BGC count, and numbers inside represent the corresponding percentage and the count of genera in which BGCs are present. The donut chart in the center displays the overall class distribution of BGCs, with corresponding colors matching the fourth layer of (b). Meanwhile, the donut chart on the right exhibits the class distribution of RiPP BGCs, with colors corresponding to the fifth layer in (b). b Layers are as follows: , the maximum likelihood phylogenetic tree based on 120 concatenate marker genes of 56 representative LAB genomes. LAB in this study covers 6 families and 56 genera under GTDB taxonomy; , the count of genomes included in this study, with being transformed with log2; , log2-transformed BGC count; , average BGC abundance in LAB genera; , average RiPPs abundance in LAB genera. In RiPPs terms, other subtypes of BGCs and hybrid BGCs are clustered into “Others”. rSAM-Modified RiPPs consist of RaS-RiPP, ranthipeptide and sactipeptide

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