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Fig. 3 | Microbiome

Fig. 3

From: Antibiotic treatment using amoxicillin-clavulanic acid impairs gut mycobiota development through modification of the bacterial ecosystem

Fig. 3

Amoxicillin/clavulanate acid treatment alters the bacterial microbiota. A–D Conventional mice treated with NaCl (Ctrl) or amoxicillin/clavulanic acid (Amox). Ctrl n = 6, Amox n = 8. A Shannon index, describing the alpha diversity of the bacterial microbiota (16S) in the fecal microbiota after 10 days of antibiotic treatment. B Beta diversity. Principal coordinate analysis of Jaccard distances with each sample colored according to the treatment. C Taxa with the largest differences (LDA > 2) in abundance by linear discriminant analysis (LEfSe) (LDA > 2). D Relative abundance (% reads) of families specifically increased by antibiotic treatment. E Antibiotic-naïve infants treated with amoxicillin due to an infection with respiratory syncytial virus (RSV). Before n = 7, during n = 7. E Enterobacteriaceae and Enterococcaceae quantity in feces after 1 to 5 days of Amox, determined by qPCR. *p < 0.05

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Microbiome

ISSN: 2049-2618

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