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Table 1 Prediction of psychological factor scores with PLS regression models based on species, KOs, and protein groups

From: Positive mood-related gut microbiota in a long-term closed environment: a multiomics study based on the “Lunar Palace 365” experiment

Mood

Metagenomic (species)

Metagenomic (KOs)

Metaproteomic (protein groups)

Q2

P

R

Q2

P

R

Q2

P

R

POMS

 Total mood disturbance

0.6861

 < 0.0001

0.8403

0.6388

 < 0.0001

0.8179

0.5112

 < 0.0001

0.7595

 Tension–anxiety

0.7718

 < 0.0001

0.8490

0.4398

 < 0.0001

0.7039

0.6664

 < 0.0001

0.7363

 Anger–hostility

0.7993

 < 0.0001

0.9075

0.4206

 < 0.0001

0.7121

0.6918

 < 0.0001

0.7782

 Fatigue–inertia

0.8901

 < 0.0001

0.9350

0.6587

 < 0.0001

0.8231

0.7415

 < 0.0001

0.8415

 Depression–dejection

0.7174

 < 0.0001

0.8364

0.5124

 < 0.0001

0.7145

0.6369

 < 0.0001

0.7545

 Confusion–bewilderment

0.9012

 < 0.0001

0.8989

0.6554

 < 0.0001

0.8369

0.7426

 < 0.0001

0.8312

 Vigour–activity

0.7896

 < 0.0001

0.8800

0.7897

 < 0.0001

0.8768

0.8127

 < 0.0001

0.9014

 Self-esteem

0.8358

 < 0.0001

0.9071

0.8221

 < 0.0001

0.8888

0.8061

 < 0.0001

0.9041

SCL-90

 SUM-SCL90

0.7262

 < 0.0001

0.8682

0.7581

 < 0.0001

0.8738

0.7225

 < 0.0001

0.7800

 Somatization

0.7413

 < 0.0001

0.8291

0.7524

 < 0.0001

0.8335

0.8439

 < 0.0001

0.8822

 Obsessive–compulsive

0.9495

 < 0.0001

0.9534

0.8352

 < 0.0001

0.8968

0.7877

 < 0.0001

0.8612

 Interpersonal sensitivity

0.8949

 < 0.0001

0.9166

0.7748

 < 0.0001

0.8400

0.8156

 < 0.0001

0.8565

 Depression

0.8498

 < 0.0001

0.9041

0.5676

 < 0.0001

0.7735

0.6934

 < 0.0001

0.8355

 Anxiety

0.8720

 < 0.0001

0.9003

0.5757

 < 0.0001

0.7749

0.7752

 < 0.0001

0.8694

 Hostility

0.6883

 < 0.0001

0.7702

0.5713

 < 0.0001

0.6475

0.8045

 < 0.0001

0.8310

 Phobic anxiety

0.9487

 < 0.0001

0.6590

0.8935

 < 0.0001

0.6529

0.8192

 < 0.0001

0.6430

 Paranoid ideation

0.6615

 < 0.0001

0.8227

0.7745

 < 0.0001

0.8438

0.7557

 < 0.0001

0.8665

 Psychoticism

0.8620

 < 0.0001

0.7869

0.8162

 < 0.0001

0.7041

0.7374

 < 0.0001

0.8101

 Additional items

0.8619

 < 0.0001

0.8627

0.6186

 < 0.0001

0.7002

0.8214

 < 0.0001

0.8490

  1. Q2, goodness of prediction based on leave-one-out cross-validated PLS regression. R,P, Spearman’s correlation coefficient (R) and P-values