Fig. 5From: Over supplementation with vitamin B12 alters microbe-host interactions in the gut leading to accelerated Citrobacter rodentium colonization and pathogenesis in miceCecal microbiota analysis of the 16S rRNA gene identified by SAMSA2 metatranscriptome analysis from the EPC experiment. Distinct clustering of microbial communities in a unweighted but not b weighted UniFrac PCoA plots (Additional file 1 Table S2). c Alpha diversity as determine by Observed, Shannon, and PD metrics showed that diversity (PD only) increased postinfection for cyanocobalamin-supplemented mice compared to control (P < 0.05). Differential expression analysis using DEseq2 of microbial taxa confirmed that the Firmicutes populations were altered from cyanocobalamin supplementation in d naïve and e infected mice (n = 6–8; bolded taxa represent a trend (P < 0.10); ***P < 0.001)Back to article page