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Fig. 5 | Microbiome

Fig. 5

From: Sputum bacterial load and bacterial composition correlate with lung function and are altered by long-term azithromycin treatment in children with HIV-associated chronic lung disease

Fig. 5

Analysis of composition of microbiomes (ANCOM2) differential abundance testing for samples at each visit and between trial arms. Taxa identified as differentially abundant between trial arms at 48 weeks (A, left panel), between AZM arm at baseline and 48 weeks (A, middle panel) and between AZM arm at 48 and 72 weeks (A, right panel). Associations were considered significant using an ANCOM detection level ≥ 0.6. Stars on the right of each bar indicate ANCOM detection levels: levels > 0.6 are presented by 1 star, > 0.7 by 2 stars, > 0.8 by 3 stars and > 0.9 by 4 stars. The raw W statistic for each comparison is shown left of the stars. The horizontal length of each bar indicates the mean centered log ratio (CLR) difference in relative abundance. B Boxplots of log10 relative abundances of bacterial genera detected as differentially abundant by ANCOM2 by trial arm at 48 weeks (B) and within AZM arm at baseline, 48 and 72 weeks (C)

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Microbiome

ISSN: 2049-2618

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