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Fig. 7 | Microbiome

Fig. 7

From: Gut microbiota-derived ursodeoxycholic acid alleviates low birth weight-induced colonic inflammation by enhancing M2 macrophage polarization

Fig. 7

Effect of macrophage depletion on UDCA-mediated alleviation of intestinal inflammation in DSS-treated mice (n = 8). A Schematic outline of the experimental design. B Daily body weight changes. C Disease activity index score. D Representative images of the colon. E Colon length. F Histology score. G Representative H&E staining (×50 magnification) of the colon sections. The mRNA expression levels of two inflammatory cytokines, IL-1β (H) and TNF-α (I), in the colon. Data are presented as means ± SEM. *P < 0.05, **P < 0.01, *** P < 0.001; #P < 0.05, relative to the DSS+UDCA group; θP < 0.05, relative to their respective clodronate treated groups

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Microbiome

ISSN: 2049-2618

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