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Fig. 5 | Microbiome

Fig. 5

From: Gut microbiota-derived ursodeoxycholic acid alleviates low birth weight-induced colonic inflammation by enhancing M2 macrophage polarization

Fig. 5

Amelioration of DSS-induced acute colitis in mice by oral administration of UDCA (n = 8). A Schematic outline of the experimental design. B Body weight changes of mice after FMT. C Disease activity index score. D Representative images of the colon. E Colon length. F Myeloperoxidase (MPO) concentrations in the colon. G Representative H&E staining (×50 magnification) and PAS staining (×50 and ×100 magnification) of the colonic sections. H Histology score of the colon. I The number of goblet cells. J The mRNA expression levels of inflammatory cytokines in the colon. K The protein levels of inflammatory cytokines in the colon. L The mRNA expression levels of BA receptors in the colon. M The protein levels of FXR in the colon. Data are presented as means ± SEM. *P < 0.05, **P < 0.01, *** P < 0.001; # P < 0.05, relative to the DSS + UDCA group

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Microbiome

ISSN: 2049-2618

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