Skip to main content
Fig. 4 | Microbiome

Fig. 4

From: Gut microbiota-derived ursodeoxycholic acid alleviates low birth weight-induced colonic inflammation by enhancing M2 macrophage polarization

Fig. 4

Colonic BA profiles of mice transplanted with the feces of LBW or NBW piglets (n = 8). A OPLS-DA score plot of the colonic BA profiles. B Relative abundances of BAs in the colonic digesta of NBW-FMT and LBW-FMT mice. C The concentration of primary BAs, secondary BAs, total BAs, and the ratio of primary BAs to total BAs, primary BAs to total BAs, and primary BAs to secondary BAs. D Violin plots of three differentially abundant colonic BAs. E Spearman correlation between the gene copy numbers of 7α-HSDH and 7β-HSDH and the concentrations of three differentially abundant BAs in the colon. F Spearman correlation between the concentration of BAs and the gene expression of proinflammatory cytokines in the colon. Data are presented as means ± SEM in panels C and D. *P < 0.05, **P < 0.01. LBW-FMT, mice transplanted with the feces of LBW piglets; NBW-FMT, mice transplanted with the feces of NBW piglets

Back to article page