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Fig. 5 | Microbiome

Fig. 5

From: Expanded catalogue of metagenome-assembled genomes reveals resistome characteristics and athletic performance-associated microbes in horse

Fig. 5

Novel insights into potential performance-enhancing microbes in racehorses. A Differences in the gut microbiota of racehorses and nonracehorses were visualized by PCoA. B Top 30 differentially abundant MAG in racehorses and nonracehorses. These MAG belong to different tax of bacteria presented on the left column. Colours from blue to red represent an increasing abundance of MAG. C Bacteria enriched in the racehorse contained key enzyme in each step of the acetate and butyrate synthesis pathway. Different colours represent different types of bacteria that contain the enzymes necessary for the pathway. The metabolic pathway and EC numbers obtained from KEGG database. D The bar chart shows the differences in key enzymes involved in acetate and butyrate synthesis between racehorses and nonracehorses. Enzymes (EC number in red) that produced acetate and butyrate are significantly enriched in the racehorse. EC numbers on horizontal axis were obtained from KEGG database. E Acetate and butyrate treatment significantly improve the exercise performance of mice. The plot shows each mouse as an individual point, and the central bar representing the mean time (n = 8). *P < 0.05, **P < 0.01, ***P < 0.001

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