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Fig. 2 | Microbiome

Fig. 2

From: Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by integrated multi-omic analyses

Fig. 2

Taxon-resolved differential abundance and gene expression in the oral microbiome in T1DM. The differences in abundance (triangles) and expression (circle) in T1DM versus healthy individuals using metagenomic and metatranscriptomic data, respectively, are shown on the volcano plot. A minimum log2 fold change of 5 (dashed vertical lines) and an adjusted p value of 0.01 (dashed horizontal line) were required (red dots). Taxa that satisfy the fold-change threshold but not the adjusted p value threshold are displayed in green. A subset of Supplementary Fig. 2 is shown in the insert in the upper-right and highlights the correlation between S. mutans activity and the expression of a target-specific bacteriocin

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