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Fig. 3 | Microbiome

Fig. 3

From: Magnetic-activated cell sorting identifies a unique lung microbiome community

Fig. 3

Increased IgG-bound bacteria in the lungs of PLWH correlate with BAL cytokine levels. We plotted IgG-bound bacteria as determined by qPCR (top) and flow cytometry (bottom) against BAL cytokine levels in PLWH. Individual dots represent the intercept between log-transformed cytokine level (x-axis) and log-transformed IgG-bound bacteria quantity (y-axis). A linear regression model was applied to assist with the visualization of the trend and quantify the degree of association. IL-8 and IL-1β correlated with increasing quantity of IgG-bound bacteria by qPCR (p = 0.003, R2 = 0.2 and p = 0.012, R2 = 0.15, respectively) and flow cytometry (p = 0.008, R2 = 0.16 and p < 0.001, R2 = 0.32, respectively)

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