Fig. 4

Phylogeny of replication initiator proteins of oyster-related circoviruses. The large tree on the left shows the phylogeny of all proteins in the clusters of the two standard Circoviridae genera recorded by the International Committee on Taxonomy of Viruses (ICTV) (Fig. S3), namely Cyclovirus (green) and Circovirus (violet). The diameter of red dots on branches represents the bootstrap value, and only values above 70 are shown. Small trees on the right are enlarged branches from the tree on the left. Background colors indicate different viral genera: light blue, Crasscircovirus; yellow, Cyclovirus; pink, Circovirus. Colors of branches indicate data origins: orange, Dataset of Oyster Virome (DOV); gray, NCBI nr database; blue, CRESS viruses from Porter et al. [72], green, circoviruses from the ICTV; violet, cycloviruses from the ICTV; red, contaminant sequences from Asplund et al. [3] and Porter et al. [72], black, other NCBI nr sequences