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Fig. 4 | Microbiome

Fig. 4

From: Limosilactobacillus reuteri and caffeoylquinic acid synergistically promote adipose browning and ameliorate obesity-associated disorders

Fig. 4

CQA alters gut microbiota compositions, especially in lactic acid bacteria enrichment. a Alpha diversity analyses based on Shannon index and Simpson index. b Principal component analysis. c Bacterial taxonomic profiling in phylum levels. d Heatmap of bacterial taxa. e, f Relative abundance of L. reuteri (%) (e) and L. lactis (%) (f) in feces detected by sequencing analysis. g Discriminative taxa determined by LEfSe between two groups (log10 LDA > 4). h Correlation of the abundance of L. reuteri (%) and L. lactis (%) with thermogenesis traits, including Ucp1 mRNA expression in adipose tissues and after 4 h cold stress and predicted MR. i Relative abundance of L. reuteri and L. lactis in anaerobic cultivation of fecal microbiota from DIO mice. j OD600 of L. reuteri and L. lactis. a–g n = 7–8/group. h n = 15–16/group. i, j n = 3/group. Data are presented as mean ± SD. *p < 0.05; **p < 0.01; ***p < 0.001. ns means not statistically significant

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